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Dr Kaivan Vaidya, consultant interventional cardiologist at One Heart Centre in Sydney (Eastern Suburbs)

Dr Kaivan Vaidya

Consultant Interventional Cardiologist
MBBS (Hons) | MMed | FRACP

Clinical Profile

Education & Training

Research

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Clinical Profile

Dr Kaivan Vaidya is an interventional cardiologist with a strong clinical focus on coronary artery disease and cardiovascular risk assessment. He specialises in coronary angiography and percutaneous coronary intervention (PCI), including coronary stenting, and provides care across both metropolitan Sydney and regional New South Wales.

His expertise and special interests include coronary physiology and the management of complex coronary artery disease. He has particular experience in calcium modification techniques and the use of intravascular imaging to optimise stent deployment and improve long-term patient outcomes.

Dr Vaidya is committed to delivering comprehensive, patient-centred cardiovascular care. He places strong emphasis on clear communication and shared decision-making, ensuring that patients are fully informed and actively involved in their treatment journey at every stage.

His hospital appointments as an interventional cardiologist include Macquarie University Hospital, Sydney Southwest Private Hospital, and Dubbo Base Hospital.

Education & Training

Dr Vaidya completed his undergraduate medical degree with Honours at the University of New South Wales, followed by resident medical officer training at Prince of Wales Hospital. He undertook advanced training in Cardiology at Royal Prince Alfred Hospital in Sydney, where he subsequently completed a dedicated two-year Interventional Cardiology Fellowship. During this time, he gained extensive experience managing a high volume of complex coronary cases, including referrals from across the state. He also completed a Master of Medicine (Clinical Epidemiology) at the University of Sydney, further strengthening his commitment to evidence-based practice.

Research

Dr Vaidya has published extensively in peer-reviewed journals, with a particular research interest in the role of atheroinflammation in coronary artery disease and its potential pharmacological modulation. His academic work has been recognised nationally, including nomination for the prestigious Ralph Reader Prize at the Cardiac Society of Australia and New Zealand in 2017.

In addition to his clinical work, Dr Vaidya is dedicated to medical education and the ongoing development of the next generation of clinicians. Through his hospital appointments, he actively supervises and mentors medical students, junior medical officers, and cardiology trainees.

Top 5 publications

  1. Vaidya K., Arnott C., Martínez G., Ng B., McCormack S., Sullivan DR., et al. Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome. A CT Coronary Angiography Study. JACC Cardiovasc Imaging. 2018 Feb; 11 (2 Pt 2): 305-316.
    – Assesses the impact of colchicine therapy on coronary plaque characteristics using CT coronary angiography in ACS patients. Shows that colchicine is associated with features of plaque stabilisation, supporting its role in secondary prevention. [https://www.jacc.org/doi/10.1016/j.jcmg.2017.06.020]
  2. Vaidya K., Tucker B., Kurup R., Khandkar C., Pandzic E., Barraclough J., Machet J., Misra A., Kavurma M., Martinez G., Rye KA., Cochran BJ., Patel S. Colchicine Inhibits Neutrophil Extracellular Trap Formation in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention. J Am Heart Assoc. 2021 Jan 5;10(1):e018993.
    – Investigates the effect of colchicine on neutrophil extracellular trap (NET) formation in ACS patients undergoing PCI, suggesting a mechanism for its cardioprotective effects. [https://www.ahajournals.org/doi/10.1161/JAHA.120.018993].
  1. Tucker B., Vaidya K., Cochran B.J., Patel S. Inflammation during Percutaneous Coronary Intervention—Prognostic Value, Mechanisms and Therapeutic Targets. Cells 2021, 10, 1391:1-28.
    – Reviews the inflammatory response triggered during percutaneous coronary intervention,  and identifies potential anti-inflammatory therapeutic targets to reduce peri-procedural complications. [https://doi.org/10.3390/cells10061391].
  1. Vaidya K., Tucker B., Patel S., Ng, M.K.C. Acute Coronary Syndromes (ACS)—Unravelling Biology to Identify New Therapies—The Microcirculation as a Frontier for New Therapies in ACS. Cells 2021, 10, 2188.
    – Explores the role of coronary microcirculation in acute coronary syndromes, highlighting it as a key driver of ongoing ischemia and adverse outcomes. Proposes novel therapeutic targets focused on microvascular dysfunction to improve outcomes beyond traditional revascularisation. [https://doi.org/10.3390/cells10092188].
  1. Wong C., Yong A., Keech A., Ada C., Vaidya K., O’Connell R., Layland J., White H., Fearon W., Ng M. Evolution of the coronary microcirculation after restoration of epicardial blood flow in ST-elevation myocardial infarction. J Am Coll Cardiol. 2022 March, 79(11): 1127-8.
    – Examines how coronary microvascular function evolves following restoration of epicardial blood flow in STEMI patients. Demonstrates that microcirculatory recovery is dynamic and may influence long-term myocardial recovery and prognosis. [https://www.jacc.org/doi/10.1016/j.jacc.2022.02.003]