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Dr Chinmay Khandkar, consultant cardiologist at One Heart Centre in Sydney (Bella Vista, Hills District)

Dr Chinmay Khandkar

Consultant Cardiologist
BMed | MD (Distinction) | MMed (ClinEpi) | FRACP

Clinical Profile

Education & Training

Research

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Clinical Profile

Dr Chinmay Khandkar is a Consultant Cardiologist and Interventional Cardiology Fellow with a special interest in coronary artery disease, coronary physiology, and preventive cardiology. He completed his Doctor of Medicine (with Distinction) at the University of New South Wales, and holds a Master of Medicine (Clinical Epidemiology) from the University of Sydney. He attained his FRACP after completing his cardiology training at Royal Prince Alfred Hospital. He has completed the American Society of Echocardiography of National Board Certification Examination. He also serves as a Clinical Associate Lecturer at the University of Sydney.

Dr Khandkar brings a holistic and evidence-based approach to cardiac care, integrating the latest research findings with compassionate, patient-centred practice. He is actively involved in translational research, to improve the diagnosis and management of patients with non-obstructive coronary artery disease. He also holds a Clinical Associate Lecturer appointment at the University of Sydney, where he contributes to medical education across both undergraduate and postgraduate programmes, and is a sought-after speaker on topics spanning coronary physiology, inflammation, and preventive cardiovascular medicine.

Education & Training

Dr Khandkar completed his Bachelor of Medicine and Doctor of Medicine with distinction at the University of New South Wales, before undertaking a Master of Medicine in Clinical Epidemiology at the University of Sydney. He subsequently completed his Fellowship of the Royal Australasian College of Physicians (FRACP) at Royal Prince Alfred Hospital, Sydney, and holds board certification in Echocardiography from the American Society of Echocardiography (ASE).

Dr Khandkar is currently completing a Doctor of Philosophy at the University of Sydney as both an NHMRC Scholar and Heart Foundation Scholar, alongside a Research and Interventional Cardiology Fellowship at Concord Repatriation General Hospital, Sydney.

Research

Dr Khandkar’s research sits at the intersection of invasive coronary physiology, intravascular imainging, machine learning, and translational cardiovascular medicine. His PhD focuses novel diagnostic modalities in interventional cardiology, especially in MINOCA and INOCA cohorts.

He serves as a lead investigator on the SCORE-CUT DCB Trial (ACTRN12625001349437), a multi-centre randomised controlled trial evaluating drug-coated balloon technology for coronary lesion preparation. He also leads the DETECT-MINOCA study (ACTRN12625000540415), which assess novel diagnostic models in these patients. His broader research interests span coronary physiology, preventive cardiology, and intravascular imaging-guided intervention.

As a Clinical Associate Lecturer at the University of Sydney, Dr Khandkar contributes to medical teaching at both undergraduate and postgraduate levels, with a particular emphasis on cardiovascular physiology, and evidence-based practice.

Selected Publications

Khandkar C, Rehan R, Ravindran J, Yong A. An updated review on therapeutic strategies in coronary microvascular dysfunction. International Journal of Cardiology. 2025; 428:133128.
This systematic review and meta-analysis evaluated current treatments for coronary microvascular dysfunction (CMD), applying a rigorous definition requiring invasive physiological confirmation.
PubMed 

Khandkar C, Madhavan MV, Weaver JC, Celermajer DS, Karimi Galougahi K. Atherothrombosis in Acute Coronary Syndromes – From Mechanistic Insights to Targeted Therapies. Cells. 2021; 10(4):865.|
A comprehensive review of the biological mechanisms driving clot formation in acute coronary syndromes, and how these insights are informing the development of more targeted antithrombotic treatments.
PubMed 

Khandkar C, Vaidya K, Patel S. Colchicine for Stroke Prevention: A Systematic Review and Meta-analysis. Clinical Therapeutics. 2019; 41(3):582–590.
A systematic review and meta-analysis examining the evidence for colchicine — an anti-inflammatory medication — as a strategy to reduce stroke risk in at-risk patients.
PubMed 

Khandkar C, Vaidya K, Karimi Galougahi K, Patel S. Low Bone Mineral Density and Coronary Artery Disease: A Systematic Review and Meta-Analysis. IJC Heart & Vasculature. 2021; 37:100891.
A systematic review and meta-analysis exploring the relationship between low bone density (osteoporosis) and coronary artery disease, with implications for cardiovascular risk assessment.
PubMed 

Khandkar C, Patel S, Karimi Galougahi K. Intravascular Imaging and Novel Techniques to Disrupt Severely Calcified Lesions. Advances in Interventional Cardiology. 2021; 17(4):337–339.
A review of intravascular imaging tools and emerging techniques — including intravascular lithotripsy and laser atherectomy — used to treat heavily calcified coronary artery blockages during interventional procedures.
PubMed Central